Brain Derived Neurotrophic Factor ( Bdnf ) - 1720 Words

I. Abstract Brain-derived neurotrophic factor (BDNF) is known to increase synaptic efficacy and promote neuronal survival. This protein is also a biomarker for impaired general cognitive function and memory. Studies have bee conducted on mice measuring the concentration of circulating, also called plasma or serum, BDNF in the blood of these animals when they exercise. Exercise has been proven to increase cognitive function and links between a large level of BDNF in the bloodstream and improved results on spatial/ cognitive testing of these rats shows that BDNF correlates to an increase in memory and cognitive abilities. In this research, studies with varying results on BDNF and exercise were taken and summarized in hopes of finding a†¦show more content†¦This protein circulates throughout the central nervous system and the concentrations can be measured in platelets (Corripio, Gà ³nzalez-Clemente, Jacobo, Silvia, Lluis, Joan, Assumpta, 2012). BDNF neurotrophins bind with hi gh affinity to its respective receptor, TrkB. These signals flow to other protein enzymes downstream of that where they regulate synaptic functioning and maintain cell viability (Tadahiro, Richards, Shingo, Naoki, Miyako, Haruki, Xin, 2014). Studies performed on rats show a crucial link between BDNF release and memory/ cognitive functioning. After two months on an HFS diet (high amounts of refined sugars and fats) the hippocampal level of BDNF and spatial learning performance in these rats was noticeable reduced. Diet-related changes were specific to the hippocampus because of its role in memory formation and that is one of the main places BDNF is produced and circulates (Molteni, Barnard, Ying, Roberts, Gà ³mez-Pinilla, 2002). These decreased cognitive functions cooresponded to a decreased amount of BDNF measured in the blood stream. It is also well documented through research that BDNF protects neurons from degeneration due to the cascade of effects it has on other proteins and e nzymes when it is released. Therefore, the reductions of BDNF that are seen resulting from an HSF diet may decrease a neurons ability to natural protect itself from degeneration (Molteni, et al., 2002). Inversely, an increased amount of serum BDNF circulating in

The Making Of A Nation - 1519 Words

The Making of a Nation The history of the United States could nearly not be written without the affirmation and recognition of the practice of slavery on American soil. Made to remain docile and obedient, the physical and psychological turmoil inflicted on imported humans seen merely as property has shaped and molded the very foundation this great nation stands upon. The life of a slave seemed to be that of a meager, inhumane being. They were worked until their muscles ached, beat until their skin fell off and humiliated until the looks of their neighbors appeared adamant. The bonding of families with husbands, wives and children alike, presented their notion of love to be inevitable. Though slaves were bound by slavery and their life was†¦show more content†¦After they were marched often hundreds of miles, it was time for them to be shipped off to sea, so that they could be sold as cheap labor to help harvest the new world. But before they were shipped off, they had to pass through a slave-tradin g station. The slave trade, which was first controlled by Portugal, was now controlled by other European nations. In the late 1600’s, Spain, Holland, England, France and Denmark were all sending ships to West Africa. The slave trade was becoming big business (Goodman, 7). Selection of the slaves by the traders was a painstaking process. Ships from England would pull up on the coast of Africa, and the captains would set off towards the coast on small ships. At a time when America was gearing up for an economic change, there was no enough labor to pump into the economy. This saw the immigration of Africans who would work in the cotton and tobacco farms. The practice was further solidified with the invention of the cotton gin in the year 1973. Some times in the 19th century, the westward expansion of America together with the increasing abolition movement that existed in the North provoked huge debates over the subject of slavery and was almost tearing the American nation apart in the Civil War that was experienced between 1861 and 1865. The Union victory was able to free four million slaves in America. All the same, the slavery legacy continued to eat into the fabric that held theShow MoreRelatedThe making of a nation806 Words   |  4 Pagesï » ¿Running head: THE MAKING OF A NATION The making of a nation Old Testament historical perspectives The making of a nation God lead the Hebrew slaves away from Egypt in the book of Exodus. The story demonstrated the progress of changes the Hebrew slaves into a nation. Several actions occur showing God worked to direct his people out of enslavement and into an existence of fortune and devotion. Several phases occurred in the process of making a nation. God chose Moses asRead MoreTechnology Is Making Its Way Into Classrooms Across The Nation And The World Essay1923 Words   |  8 Pages As our world becomes increasingly globalized and reliant on new and innovative technologies, it is no wonder that technology is making its way into classrooms both across the nation and the world. When I was secondary school, we used technology every so often to complete various assignments, with many of my classes often taking a trip to the computer labs in my school. However, much of our everyday class work was still done the â€Å"traditional† way—that is, using a pen and paper—and once again theRea d MoreDonica Belisles Retail Nation: Department Stores and the Making of Modern Canada894 Words   |  4 PagesDonica Belisles Retail Nation: Department Stores and the Making of Modern Canada is a very brief and concise book. It is able to deal with the major social and economic topics from the early-twentieth century from the perspective of massive retailers. 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However, between the two entities, there will always existsRead MoreAmerica s Criminal Justice System896 Words   |  4 PagesAccording to Maxeiner (2012); their area unit two principal objectives of criminal justice, to set up the difficulty for effective decision-making and therefore the ability to come to a decision. These a number of the cited as a number of the most things that show however Germany s criminal justice system contrasts with the America s criminal justice system. supported this; this essay are going to be comparison at a number of the basic variations between Americaâ €™s and Germany’s scheme (MaxeinerRead MoreUnited Nations : An Establishment That Brings 193 Countries1404 Words   |  6 PagesUnited Nations is an establishment that brings 193 countries together in one building. After the failure of League of Nations, in 1945, President Franklin D. Roosevelt pitched the idea of United Nations in order to bring worldwide peace. After the ratification of the charter of UN, it began to properly function. The head quarter of United Nations resides in Manhattan, New York (www.un.org). In this building the members of the UN hold General assemblies, conferences, and make decisions regarding theRead MoreGlobal Economic Problems1111 Words   |  5 Pagesdiseases 7. To ensure environmental sustainability 8. To develop a global partnership for development. (United Nations 2010, Murphy, 2017, p.2) As of the 2015, while the attainment of the goals remain dubious and doubtful much progress has been made by very few countries, while others are still straggling as empty promises of a better tomorrow (Bartlett, 2017, p.1). Some nations are making enormous progress to lift their citizens from the hollows of poverty. Consequently, billions of people are noRead MoreThe Phenomenon of Globalization1498 Words   |  6 Pagesbe seen but the fact that they are taking place cannot be denied. 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Digestive disorders (liver) Essay Example For Students

Digestive disorders (liver) Essay Digestive DisordersAmebic Dysentry is a disorder in which there is anaccumulation of pus located in the liver. This is usually caused byan internal parasite or organism. When dealing with this liverdisease there are a few symptoms to look out for. Jaundice, whichis something that will make your skin and eyes go yellow is asymptom of Amebic Dysentry. Other symptoms to look out forare chills, a high fever, sweating, diarrhea, loss of appetite, weightloss, abdominal pain, possible joint pain and an all around basicdiscomfort. Amebic Dysentry is caused by the same micro-organism thatcauses a variety of intestine infections. This organism is carriedthrough the blood stream to the liver to where the abscess isformed. For starters, the collection of pus is the bodies whiteblood cells forming to protect the liver. However, it collects toomuch and that is how the abscess is formed. When you arediagnosed with amebic liver you are very likely to also have anintestinal infection from the disease as well. This is not true for allcases though. Most cases in which both occur are in places ofhigh temperatures and poor sanitation. Africa, Latin America,Southeast Asia, and India have many health problemsassociated with the disease. The most common way to get thisdisease is from one person to another. The other most commonway is through unhealthy food and badly sanitized water. Noteating properly and excessive drinking will only worsen thedisease. There are many ways that you can help prevent getting thisdisease. If you go to a foreign country, especially in the tropics,always drink purified water, always peel fruit and vegetables, andcook your food at any time possible. If you think that you may have amebic liver, you should geta liver scan and an ultrasound treatment. If you are diagnosedwith it the usual treatment for this is Antimicrobial therapy is theway to go. The first step taken is they will drain the abscess (puscollection) to relieve some discomfort. After that, antibiotics andmedication will get rid of the organism. If you do not get medical attention for this the abscess mayrupture and infect your insides, rupture into the lungs and hence cause death to occur. So as you can see, attending to the disease isvery, very, important.

Young Adulthood The Impact of Infertility an Example by

Young Adulthood: The Impact of Infertility In the research of human development, there may not be anyone who studied more closely or spoke more eloquently about the stages of psychosocial human development than Erik Erikson. He characterized young adulthood as the area or time of a person's life from about age 18 to age 35, when one is most apt to be focused on the challenges of intimacy and solidarity versus isolation. The main drive to be successful during this time period is to find and express love, to become affiliated with both a romantic partner as well as friendships through mutually satisfying relationships. Erikson believed that if one is successful in negotiating or moving through this stage, then one can experience intimacy on a deep level. Need essay sample on "Young Adulthood: The Impact of Infertility" topic? We will write a custom essay sample specifically for you Proceed However, if one is not successful, then one may become isolated, distant from others. Erikson suggested that if one isn't able to create satisfying relationships with ease, then the world can seem to shrink as one defensively moves away from instead of toward others, perhaps in feeling falsely superior or inferior, lacking true self identity and self worth (Thies & Travers). College Students Frequently Tell Us: How much do I have to pay someone to write my essay now? Professional writers recommend: Follow Essaylab Writing Service Buy Essays Online Paper Writers For Hire College Paper Writing Service Reviews Write Papers For Money However, if one moves into and through young adulthood successfully, having found a loving romantic partner, it's very interesting to take the example of infertility into the realm. One has found the perfect partner, the perfect love, and the two people are getting along rather well, secure in their identities and in their mutual love and respect for themselves and one another. This stage is then thought of as having been navigated successfully, however, the element of fertility is also essential on a basic level to having successfully delivered the promised goods to one's life mate. With the increase in infertility in the child bearing age population which includes young adulthood, it's essential that one consider the ramifications of infertility on people moving through this stage of life. Does one successfully complete the stage if one has found the perfect mate yet is then severely troubled by the more biological stumbling block of the incapacity of being able to reproduce and be ar children? It's important to focus on all elements of moving though life successfully. In this case, a more biological disability restricts the individual, against his or her will, from being able to accomplish what can be a very important task of young adulthood, reproduction. The bio-psycho-social stage of young adulthood must be viewed from all angles, because biology, psychology, and sociology are helplessly intertwined and always mutually affecting one another. In the case of the young person who is unable to fertilize and conceive, the newfound love relationship may be forever tarnished or even subject to loss. For the practitioner working with individuals who have moved into or through young adulthood successfully in regard to having found a mutually satisfying romantic relationship, it's important to note the sensitive significance of the issue of infertility. A couple facing the fact that the love they share and give one another, physically, emotionally, and spiritually, yields no hope, no fruit in their quest for children, may very well dash their ability to really move through this stage successfully, sometimes dissolving a once happy relationship based solely on the desire for children. It's important for practitioners to know that sometimes, even if the love is there between two people, the possibility remains strong for the relationship to fall apart, based on the eventual urge of one or both people to find success with a new person, a new mate, whose fertility is not compromised. This type of event can be heart wrenching and bittersweet for all parties involved, and, even if the co uple does stay together, the question remains open for this stage and following stages... will it really be successful References Thies, K. & Travers, J. (2006). Handbook of Human Development for Health Care Professionals. Jones & Bartlett Publishers.